Preformulation

A solid understanding of a compound’s physicochemical properties is the keystone to developing an elegant and robust dosage form.  Velesco’s experienced team of physical chemists can quickly identify the properties of your molecule that will enhance a product’s performance.  Furthermore, they can recommend ways to improve product performance through alternative chemical and/or physical forms.

A wide variety of characterization techniques are employed by Velesco’s scientists to ensure that the required properties of your compound are accurately determined.  These include:

  • Excipient compatability

  • Hygroscopicity determination

  • Polymorph identification

  • Crystal size and habit

  • pH solubility profile

  • cLogP determination

  • Bulk/tap density

  • Flowability

  • Compressibility

Preformulation
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