Drug Formulation Challenge 3

High Concentration Drug Formulation Development for Compounds with Low Solubility using Microemulsions

 

Our client had a poorly soluble compound for which they wanted a clear solution/microemulsion at high concentration for oral use in toxicology studies.

  

Velesco solution: 

  • Within one day, Velesco developed a drug formulation that met the client's target concentration, was a lipid-based self-emulsifying drug delivery system (SEDDS), stable for three weeks at ambient storage and had potential for further development as a soft-gel formulation.
  • Client requested development of additional oil/water microemulsion formulations at high concentration.  Velesco quickly developed two additional formulations to meet these requirements.  The oil/water microemulsion also demonstrated good stability.

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Velesco has expanded our analytical facilities in a new Wixom, Michigan location with the help of the Bank of Ann Arbor Technology Industry Group. Read the press release here.

  

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Velesco's work published 

 Outsourcing Formulation Development & Manufacturing:

Using a Single Provider Reduces Costs & Risk

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