Drug Formulation Challenge 3

High Concentration Drug Formulation Development for Compounds with Low Solubility using Microemulsions

 

Our client had a poorly soluble compound for which they wanted a clear solution/microemulsion at high concentration for oral use in toxicology studies.

  

Velesco solution: 

  • Within one day, Velesco developed a drug formulation that met the client's target concentration, was a lipid-based self-emulsifying drug delivery system (SEDDS), stable for three weeks at ambient storage and had potential for further development as a soft-gel formulation.
  • Client requested development of additional oil/water microemulsion formulations at high concentration.  Velesco quickly developed two additional formulations to meet these requirements.  The oil/water microemulsion also demonstrated good stability.

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News and Events

 

Lisa Crandall, MS, and Peter Angus, PhD, spoke with Pharmaceutical Technology about the best practices in stability testing.  Read the interview here.

 

                                                                              Velesco has expanded our analytical facilities in a new Wixom, Michigan location with the help of the Bank of Ann Arbor Technology Industry Group.                          Read the press release here.

  

CEO Dave Barnes has been published in a new Pharmoutsourcing article on Clinical Trial Materials and Manufacturing! 

  

2 new job postings! Careers 

  

Velesco's work published 

  Formulation Development & Manufacturing:

Using a Single Provider Reduces Costs & Risk

Read it here.

  

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