Drug Formulation Challenge 3

High Concentration Drug Formulation Development for Compounds with Low Solubility using Microemulsions

 

Our client had a poorly soluble compound for which they wanted a clear solution/microemulsion at high concentration for oral use in toxicology studies.

  

Velesco solution

  • Within one day, Velesco developed a drug formulation that met the client's target concentration, was a lipid-based self-emulsifying drug delivery system (SEDDS), stable for three weeks at ambient storage and had potential for further development as a soft-gel formulation.
  • Client requested development of additional oil/water microemulsion formulations at high concentration.  Velesco quickly developed two additional formulations to meet these requirements.  The oil/water microemulsion also demonstrated good stability.

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