Analytical Method Challenge 3

Large Potential Dose Range of Low Solubility Compound

 

A small virtual pharma manufacturing client needed a drug product release method for a very poorly soluble drug with a wide potential dosing range (300X).

 

Velesco solution:

  • Velesco created a drug product extraction and HPLC method that encompassed the whole dose range.
  • A successful dissolution method was developed using surfactants.
  • A stability indicating program was undertaken and the client was able to file an IND with an eight-week stability.

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News and Events

 

Lisa Crandall, MS, and Peter Angus, PhD, spoke with Pharmaceutical Technology about the best practices in stability testing.  Read the interview here.

 

                                                                              Velesco has expanded our analytical facilities in a new Wixom, Michigan location with the help of the Bank of Ann Arbor Technology Industry Group.                          Read the press release here.

  

CEO Dave Barnes has been published in a new Pharmoutsourcing article on Clinical Trial Materials and Manufacturing

  

2 new job postings! Careers 

  

Velesco's work published 

  Formulation Development & Manufacturing:

Using a Single Provider Reduces Costs & Risk

Read it here.

  

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